Here’s how politicians and activists are reacting to the end of Roe v. Wade

Massachusetts Senator Edward J. Markey tweeted that, “The overturning of Roe v. Wade and Casey v. Planned Parenthood is an egregious and overtly political act that jeopardizes the health, safety, and freedom of millions of Americans. Abolish the filibuster, pass the Women’s Health Protection Act, and expand the Court now.”

Katherine Clark, the House representative for Massachusetts 5th Congressional District and a member of House Democratic leadership, tweeted that the move “brings us to the horrifying reality of government-mandated pregnancy — we are now living in a dystopian nightmare. Forced pregnancy is morally abhorrent, and this decision will set women back decades. But we are not powerless. We will fight.”

Former president Barack Obama chimed in, too. “Today, the Supreme Court not only reversed nearly 50 years of precedent, it relegated the most intensely personal decision someone can make to the whims of politicians and ideologues—attacking the essential freedoms of millions of Americans,” he tweeted.

Former First Lady Michelle Obama added on Twitter that she, too, was “heartbroken.”

”This is what our mothers and grandmothers and great-grandmothers lived through, and now we are here again.”

Boston Mayor Michelle Wu tweeted out in support of those seeking abortions and linked to an Act Blue fund that helps support abortion providers nationwide.

“To all those who have received abortion care, considered getting an abortion, or supported a loved one who needed care: I stand with you. Abortion is crucial healthcare. Every level of government, from city to federal, needs to stand up now to protect access to care.”

Massachusetts Senator Elizabeth Warren put out a statement that doubled as a rallying call. “We will not go back. Not now. Not ever.”

Alexandria Ocasio-Cortez, a House representative from New York and a prominent progressive voice, tweeted out a screenshot from a prior Instagram story, calling for hope and strength in the face of the Roe decision — and other dismal news.

“There is no doubt that things are bad. ... But that does not preclude the fact that slowly but surely, some good can be growing.”

Massachusetts Attorney General and gubernatorial candidate Maura Healy said today is “dark day in our history.”

Former Vice President Mike Pence, a staunch antiabortion advocate, released a statement declaring that “Life Won.”

”Now that Roe v. Wade has been consigned to the ash heap of history, a new arena in the cause of life has emerged, and it is incumbent on all who cherish the sanctity of life to resolve that we will take the defense of the unborn and the support for women in crisis pregnancy centers to every state in America.”

He went on to call for anti-abortion laws in all 50 states: “Having been given this second chance for Life, we must not rest and must not relent until the sanctity of life is restored to the center of American law in every state in the land.”

Senate Republican Leader Mitch McConnell, who has spent his career fighting to get conservative justices appointed to the highest court in the land, touted the Supreme Court ruling as “courageous and correct.” In a statement, he said the decision righted past wrongs.

“The Court has corrected a terrible legal and moral error, like when Brown v. Board overruled Plessy v. Ferguson. The Justices applied the Constitution. They carefully weighed the complex factors regarding precedent. The Court overturned mistaken rulings that even liberals have long admitted were incoherent, restoring the separation of powers.”

Jesse Mermell, the past president of the Alliance for Business Leadership and a former executive at Planned Parenthood, tweeted: “The far right that controls #SCOTUS was clear that they were coming for #abortion, & here we are. They have also been clear that they are coming for marriage equality, birth control, interracial marriage, & more. The impact of today’s #Dobbs ruling extends way beyond #abortion.”

House Speaker Nancy Pelosi placed the blame for the decision on “Donald Trump, Mitch McConnell, the Republican Party & their supermajority on the Supreme Court” in a tweet.

“Today, the Republican-controlled Supreme Court has achieved the GOP’s dark and extreme goal of ripping away women’s right to make their own reproductive health decisions,” she tweeted.

State Representative Tami Gouveia, a Democrat from Acton and candidate for lieutenant governor, tweeted that “The Supreme Court just took two big swipes against civil rights while simultaneously expanding access to guns,” citing yesterday’s ruling that struck down a New York law that restricted the ability to carry handguns.

“As tired as I am, I know we can’t quit,” she continued. ”There is too much on the line.”

Boston city councilor-turned-Congresswoman Ayanna Pressley released a statement saying that the end of Roe will worsen existing discrepancies in healthcare, particularly for Black and brown families.

The Massachusetts Democrat reminded residents that the procedure remains protected in the state — and that any existing appointments will continue as planned.

“Let me be clear: by restricting abortion access, this Court is putting the health of the most vulnerable people at risk and we must use every tool, at every level of government, to protect reproductive rights and save lives.”

Stacey Abrams, the Democratic nominee for governor in Georgia, tweeted that she is “appalled. Enraged. Undaunted & ready to fight back.” A six week ban is currently pending in the state.

Vermont Senator Bernie Sanders advocated for politicians to take steps to resurrect abortion protections.

“Overturning Roe v. Wade and denying women the right to control their own bodies is an outrage and in defiance of what the American people want. Democrats must now end the filibuster in the Senate, codify Roe v. Wade, and once again make abortion legal and safe,” the former presidential contender tweeted.

Missouri Congresswoman Cori Bush tweeted that reproductive rights are a fundamental part of public health.

“Abortion care IS health care. It was so before this. And it will remain so after this. We don’t care what a far-right extremist Supreme Court that is in a crisis of legitimacy says. Your racist, sexist, classist ruling won’t stop us from accessing the care we need,” she wrote.

International figures weighed in as well. Nicola Sturgeon, the first minister of Scotland, said the US ruling could have dire consequences in other countries contemplating the future of abortion.

“One of the darkest days for women’s rights in my lifetime,” she tweeted. “Obviously the immediate consequences will be suffered by women in the US - but this will embolden anti-abortion & anti-women forces in other countries too. Solidarity doesn’t feel enough right now — but it is necessary.”

Cardinal Seán O’Malley, the archbishop of Boston, commended the decision as “encouraging” for those who have “spoken, written, worked, marched, and prayed to reverse Roe v. Wade.”

“This decision will create the possibility of protecting human life from conception; it calls us to recognize the unique burden faced by women in pregnancy; and it challenges us as a nation to work together to build up more communities of support — and available access to them — for all women experiencing unplanned pregnancies.”

Laura Rankin, the author of “Bodies on the Line,” tweeted that there remains a path forward for activists fighting for abortion protections.

“This is devastating, an absolute national tragedy. But know that this isn’t the end of this fight, that activists and organizers are diligently working to continue access to safe abortion,” she said.

Diti Kohli can be reached at diti.kohli@globe.com.Follow her on Twitter @ditikohli_.